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Structure and in vitro replication of DNA templates containing 7,8-dihydro-8-oxoadenine.

Adenine residues in DNA are oxidized under the action of ionizing radiation at the C-8 position to give 7,8-dihydro-8-oxoadenine. The formation of this lesion can be considered a cause of mutations and carcinogenesis. Oligodeoxyribonucleotides 39 and 47 bases long containing a single 7,8-dihydro-8-o...

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Publicat a:Nucleic Acids Res
Autors principals: Guschlbauer, W, Duplaa, A M, Guy, A, Téoule, R, Fazakerley, G V
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1991
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328100/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1851559/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.8.1753
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