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Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine
Intestinal immunoglobulin A (IgA) ensures host defense and symbiosis with our commensal microbiota. Yet previous studies hint at a surprisingly low diversity of intestinal IgA, and it is unknown to what extent the diverse Ig arsenal generated by somatic recombination and diversification is actually...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3280880/ https://ncbi.nlm.nih.gov/pubmed/22249449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111980 |
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