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The Role of Incretin Therapy at Different Stages of Diabetes

The pathogenetic mechanisms causing type 2 diabetes are complex, and include a significant reduction of the incretin effect. In patients with type 2 diabetes, GLP-1 secretion may be impaired, while GIP secretion seems unaffected. In contrast, the insulinotropic activity of GIP is severely altered, w...

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Bibliographic Details
Main Author: Cernea, Simona
Format: Artigo
Language:Inglês
Published: SBDR - Society for Biomedical Diabetes Research 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280667/
https://ncbi.nlm.nih.gov/pubmed/22262070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2011.8.323
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