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Transgenic strategy for identifying synaptic connections in mice by fluorescence complementation (GRASP)

In the “GFP reconstitution across synaptic partners” (GRASP) method, non-fluorescent fragments of GFP are expressed in two different neurons; the fragments self-assemble at synapses between the two to form a fluorophore. GRASP has proven useful for light microscopic identification of synapses in two...

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Detalhes bibliográficos
Main Authors: Yamagata, Masahito, Sanes, Joshua R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280602/
https://ncbi.nlm.nih.gov/pubmed/22355283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2012.00018
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