Inborn errors of anti-viral interferon immunity in humans

The three types of interferon (IFNs) are essential for immunity against at least some viruses in the mouse model of experimental infections, type I IFNs displaying the broadest and strongest anti-viral activity. Consistently, human genetic studies have shown that type II IFN is largely redundant for...

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Main Authors: Sancho-Shimizu, Vanessa, de Diego, Rebeca Perez, Jouanguy, Emmanuelle, Zhang, Shen-Ying, Casanova, Jean-Laurent
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280408/
https://ncbi.nlm.nih.gov/pubmed/22347990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2011.10.016
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