Role of Complement 3a in the Synthetic Phenotype and Angiotensin II-Production in Vascular Smooth Muscle Cells From Spontaneously Hypertensive Rats

BACKGROUND: Spontaneously hypertensive rats (SHR)-derived vascular smooth muscle cells (VSMCs) show exaggerated growth with a synthetic phenotype and angiotensin II (Ang II)-production. To evaluate the contribution of complement 3 (C3) or C3a toward these abnormalities in SHR, we examined effects of...

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Hlavní autoři: Han, Ying, Fukuda, Noboru, Ueno, Takahiro, Endo, Morito, Ikeda, Kazuya, Xueli, Zhou, Matsumoto, Taro, Soma, Masayoshi, Matsumoto, Koichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
Blood Vessels
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280391/
https://ncbi.nlm.nih.gov/pubmed/22089112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajh.2011.214
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