Plk1 and CK2 Act in Concert to Regulate Rad51 during DNA Double Strand Break Repair

Homologous recombination (HR) plays an important role in the maintenance of genome integrity. HR repairs broken DNA during S and G2 phases of the cell cycle but its regulatory mechanisms remain elusive. Here, we report that Polo-like kinase 1 (Plk1), which is vital for cell proliferation and is freq...

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Bibliographic Details
Main Authors: Yata, Keiko, Lloyd, Janette, Maslen, Sarah, Bleuyard, Jean-Yves, Skehel, Mark, Smerdon, Stephen J., Esashi, Fumiko
Format: Artigo
Language:Inglês
Published: Cell Press 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280358/
https://ncbi.nlm.nih.gov/pubmed/22325354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.12.028
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