Antimetastatic Effects of Norcantharidin on Hepatocellular Carcinoma by Transcriptional Inhibition of MMP-9 through Modulation of NF-kB Activity

BACKGROUND: The rate of morbidity and mortality of hepatocellular carcinoma (HCC) in Taiwan has not lessened because of difficulty in treating tumor metastasis. Norcantharidin (NCTD) is currently used as an anticancer drug for hepatoma, breast cancer, and colorectal adenocarcinoma. NCTD possesses va...

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Bibliographic Details
Main Authors: Yeh, Chao-Bin, Hsieh, Ming-Ju, Hsieh, Yi-Hsien, Chien, Ming-Hsien, Chiou, Hui-Ling, Yang, Shun-Fa
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280344/
https://ncbi.nlm.nih.gov/pubmed/22363545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031055
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