A Francisella tularensis Live Vaccine Strain That Improves Stimulation of Antigen-Presenting Cells Does Not Enhance Vaccine Efficacy

Vaccination is a proven strategy to mitigate morbidity and mortality of infectious diseases. The methodology of identifying and testing new vaccine candidates could be improved with rational design and in vitro testing prior to animal experimentation. The tularemia vaccine, Francisella tularensis li...

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Autori principali: Schmitt, Deanna M., O'Dee, Dawn M., Horzempa, Joseph, Carlson, Paul E., Russo, Brian C., Bales, Jacqueline M., Brown, Matthew J., Nau, Gerard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280287/
https://ncbi.nlm.nih.gov/pubmed/22355343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031172
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