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A Comparison of rpoB and 16S rRNA as Markers in Pyrosequencing Studies of Bacterial Diversity

BACKGROUND: The 16S rRNA gene is the gold standard in molecular surveys of bacterial and archaeal diversity, but it has the disadvantages that it is often multiple-copy, has little resolution below the species level and cannot be readily interpreted in an evolutionary framework. We compared the 16S...

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Autores principales: Vos, Michiel, Quince, Christopher, Pijl, Agata S., de Hollander, Mattias, Kowalchuk, George A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280256/
https://ncbi.nlm.nih.gov/pubmed/22355318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030600
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