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Assessing the joint effect of population stratification and sample selection in studies of gene-gene (environment) interactions

BACKGROUND: It is well known that the presence of population stratification (PS) may cause the usual test in case-control studies to produce spurious gene-disease associations. However, the impact of the PS and sample selection (SS) is less known. In this paper, we provide a systematic study of the...

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Detalhes bibliográficos
Main Authors: Cheng, KF, Lee, JY
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280159/
https://ncbi.nlm.nih.gov/pubmed/22284162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-13-5
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