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APOE modifies the association between Aβ load and cognition in cognitively normal older adults

OBJECTIVE: To determine the relationship between β-amyloid (Aβ) load as measured by [(11)C]–Pittsburgh compound B (PiB) PET and cognitive function in cognitively normal older adults. METHODS: We studied 408 cognitively normal older adults who participated in the population-based Mayo Clinic Study of...

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Detalhes bibliográficos
Main Authors: Kantarci, K., Lowe, V., Przybelski, S.A., Weigand, S.D., Senjem, M.L., Ivnik, R.J., Preboske, G.M., Roberts, R., Geda, Y.E., Boeve, B.F., Knopman, D.S., Petersen, R.C., Jack, C.R.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280056/
https://ncbi.nlm.nih.gov/pubmed/22189452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e31824365ab
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