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Host Glycan Recognition by a Pore Forming Toxin

An exposed F-type lectin domain fused to the N-terminus of a cholesterol-dependent cytolysin scaffold allows Streptococcus mitis Lectinolysin to cluster at fucose-rich sites on target cell membranes, thereby leading to increased pore-forming toxin activity. In this issue of Structure, Feil and cowor...

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Detalles Bibliográficos
Main Authors: Bouyain, Samuel, Geisbrecht, Brian V.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279720/
https://ncbi.nlm.nih.gov/pubmed/22325766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.01.013
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