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Hybridization of synthetic oligodeoxyribonucleotides to phi chi 174 DNA: the effect of single base pair mismatch.

Oligodeoxyribonucleotides complementary to the DNA of the wild type (wt) bacteriophage phi chi 174 have been synthesized by the phosphotriester method. The oligomers, 11, 14, and 17 bases long, are complementary to the region of the DNA which accounts for the am-3 point mutation. When hybridized to...

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Detalhes bibliográficos
Main Authors: Wallace, R B, Shaffer, J, Murphy, R F, Bonner, J, Hirose, T, Itakura, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC327955/
https://ncbi.nlm.nih.gov/pubmed/158748
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