Global Levels of Histone Modifications in Peripheral Blood Mononuclear Cells of Subjects with Exposure to Nickel

Background: Occupational exposure to nickel (Ni) is associated with an increased risk for lung and nasal cancers. Ni compounds exhibit weak mutagenic activity, cause gene amplification, and disrupt cellular epigenetic homeostasis. However, the Ni-induced changes in global histone modification levels...

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Main Authors: Arita, Adriana, Niu, Jingping, Qu, Qingshan, Zhao, Najuan, Ruan, Ye, Nadas, Arthur, Chervona, Yana, Wu, Fen, Sun, Hong, Hayes, Richard B., Costa, Max
Format: Artigo
Sprog:Inglês
Udgivet: National Institute of Environmental Health Sciences 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279455/
https://ncbi.nlm.nih.gov/pubmed/22024396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1104140
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