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Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens
Anaplastic gliomas, the most common and malignant of primary brain tumors, frequently contain activating mutations and amplifications in promigratory signal transduction pathways. However, targeting these pathways with individual signal transduction inhibitors does not appreciably reduce tumor invas...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3279383/ https://ncbi.nlm.nih.gov/pubmed/22219380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-01-0039 |
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