Evaluation of C-reactive protein prior to and on-treatment as a predictor of benefit from atorvastatin: observations from the Anglo-Scandinavian Cardiac Outcomes Trial

AIMS: We tested whether on-statin C-reactive protein is associated with cardiovascular (CV) outcome in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). METHODS AND RESULTS: ASCOT randomized a subset of 4853 patients with total cholesterol ≤6.5 mmol/L (250 mg/dL) to atorvastatin or placebo. In...

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Autori principali: Sever, Peter S., Poulter, Neil R., Chang, Choon L., Hingorani, Aroon, Thom, Simon A., Hughes, Alun D., Welsh, Paul, Sattar, Naveed
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Clinical Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279312/
https://ncbi.nlm.nih.gov/pubmed/21798891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehr262
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