Prevalence of osteoporosis and vertebral fractures in acromegalic patients

Growth Hormone (GH) and Insulin-like Growth Factor (IGF-1) stimulate proliferation, differentiation and extracellular matrix production in osteoblastic cells. GH and IGF-1 also stimulate recruitment and bone resorption activity in osteoclastic cells. A chronic systemic GH and IGF-1 excess produces a...

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Autors principals: Padova, Giuseppina, Borzì, Graziella, Incorvaia, Laura, Siciliano, Guido, Migliorino, Valentina, Vetri, Mario, Tita, Patrizia
Format: Artigo
Idioma:Inglês
Publicat: CIC Edizioni Internazionali 2011
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279059/
https://ncbi.nlm.nih.gov/pubmed/22461828
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