Administration of Pigment Epithelium-Derived Factor Inhibits Left Ventricular Remodeling and Improves Cardiac Function in Rats with Acute Myocardial Infarction

Oxidative stress and inflammation are involved in cardiac remodeling after acute myocardial infarction (AMI). We have found that pigment epithelium-derived factor (PEDF) inhibits vascular inflammation through its anti-oxidative properties. However, effects of PEDF on cardiac remodeling after AMI rem...

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Main Authors: Ueda, Shin-ichiro, Yamagishi, Sho-ichi, Matsui, Takanori, Jinnouchi, Yuko, Imaizumi, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278887/
https://ncbi.nlm.nih.gov/pubmed/21281791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.10.018
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