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BPDA2d—a 2D global optimization-based Bayesian peptide detection algorithm for liquid chromatograph–mass spectrometry

Motivation: Peptide detection is a crucial step in mass spectrometry (MS) based proteomics. Most existing algorithms are based upon greedy isotope template matching and thus may be prone to error propagation and ineffective to detect overlapping peptides. In addition, existing algorithms usually wor...

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Autors principals: Sun, Youting, Zhang, Jianqiu, Braga-Neto, Ulisses, Dougherty, Edward R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278754/
https://ncbi.nlm.nih.gov/pubmed/22155863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr675
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