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Effect of lucanthone (miracil D) on transcription of ribosomal RNA genes from Tetrahymena in vivo and in vitro.

Addition of lucanthone (1-5 mug/ml) to cultures of Tetrahymena results in a preferential inhibition of the synthesis of ribosomal RNA. Transcriptional studies with isolated nucleoli from Tetrahymena demonstrate that the endogenous RNA polymerases of the r-chromatin (chromatin form of rDNA) do not re...

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Hlavní autoři: Westergaard, O, Gocke, E, Nielsen, O F, Leer, J C
Médium: Artigo
Jazyk:Inglês
Vydáno: 1979
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC327861/
https://ncbi.nlm.nih.gov/pubmed/111229
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