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Chronic intermittent hypoxia induces local inflammation of the rat carotid body via functional upregulation of proinflammatory cytokine pathways

Maladaptive changes in the carotid body (CB) induced by chronic intermittent hypoxia (IH) account for the pathogenesis of cardiovascular morbidity in patients with sleep-disordered breathing. We postulated that the proinflammatory cytokines, namely interleukin (IL)-1β, IL-6 and tumor necrosis factor...

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Bibliografiske detaljer
Main Authors: Lam, Siu-Yin, Liu, Yu, Ng, Kwong-Man, Lau, Chi-Fai, Liong, Emily C., Tipoe, George L., Fung, Man-Lung
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278607/
https://ncbi.nlm.nih.gov/pubmed/22187044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00418-011-0900-5
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