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Inhibition of cell growth and induction of apoptosis in ovarian carcinoma cell lines CaOV3 and SKOV3 by natural withanolide Withaferin A

OBJECTIVE: Withaferin A, a natural withanolide, has shown anti-cancer properties in various cancers including breast cancer, but its effects in ovarian cancer remain unexplored. Notch 1 and Notch3 are critically involved in ovarian cancer progression. We decided to examine the effects of Withaferin...

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Detalhes bibliográficos
Main Authors: Zhang, Xuan, Samadi, Abbas K., Roby, Katherine F., Timmermann, Barbara, Cohen, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278582/
https://ncbi.nlm.nih.gov/pubmed/22188785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2011.11.044
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