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Loss of Autophagy in Proopiomelanocortin Neurons Perturbs Axon Growth and Causes Metabolic Dysregulation
The hypothalamic melanocortin system, which includes neurons that produce proopiomelanocortin (POMC)-derived peptides, is a major negative regulator of energy balance. POMC neurons begin to acquire their unique properties during neonatal life. The formation of functional neural systems requires mass...
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Hauptverfasser: | , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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2012
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278575/ https://ncbi.nlm.nih.gov/pubmed/22285542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.12.016 |
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