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Loss of Autophagy in Proopiomelanocortin Neurons Perturbs Axon Growth and Causes Metabolic Dysregulation

The hypothalamic melanocortin system, which includes neurons that produce proopiomelanocortin (POMC)-derived peptides, is a major negative regulator of energy balance. POMC neurons begin to acquire their unique properties during neonatal life. The formation of functional neural systems requires mass...

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Détails bibliographiques
Auteurs principaux: Coupé, Bérengère, Ishii, Yuko, Dietrich, Marcelo O, Komatsu, Masaaki, Horvath, Tamas L., Bouret, Sebastien G.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278575/
https://ncbi.nlm.nih.gov/pubmed/22285542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.12.016
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