SIVmac239 MVA Vaccine with and without a DNA Prime, Similar Prevention of Infection by a Repeated Dose SIVsmE660 Challenge Despite Different Immune Responses

BACKGROUND: Vaccine regimens using different agents for priming and boosting have become popular for enhancing T cell and Ab responses elicited by candidate HIV/AIDS vaccines. Here we use a simian model to evaluate immunogenicity and protective efficacy of a recombinant modified vaccinia Ankara (MVA...

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Autori principali: Lai, Lilin, Kwa, Sue-Fen, Kozlowski, Pamela A., Montefiori, David C., Nolen, Tracy, Hudgens, Michael G., Johnson, Welkin E., Ferrari, Guido, Hirsch, Vanessa M., Felber, Barbara K., Pavlakis, George N., Earl, Patricia L., Moss, Bernard, Amara, Rama Rao, Robinson, Harriet L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278564/
https://ncbi.nlm.nih.gov/pubmed/22178526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.12.026
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