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Ion channels and schizophrenia: a gene set-based analytic approach to GWAS data for biological hypothesis testing

Schizophrenia is a complex genetic disorder. Gene set-based analytic (GSA) methods have been widely applied for exploratory analyses of large, high-throughput datasets, but less commonly employed for biological hypothesis testing. Our primary hypothesis is that variation in ion channel genes contrib...

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Detalhes bibliográficos
Main Authors: Askland, Kathleen, Read, Cynthia, O’Connell, Chloe, Moore, Jason H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278516/
https://ncbi.nlm.nih.gov/pubmed/21866342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-011-1082-x
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