Contrasting Roles for CD4 vs. CD8 T-Cells in a Murine Model of Virally Induced “T1 Black Hole” Formation

MRI is sensitive to tissue pathology in multiple sclerosis (MS); however, most lesional MRI findings have limited correlation with disability. Chronic T1 hypointense lesions or “T1 black holes” (T1BH), observed in a subset of MS patients and thought to represent axonal damage, show moderate to stron...

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Main Authors: Pirko, Istvan, Chen, Yi, Lohrey, Anne K., McDole, Jeremiah, Gamez, Jeffrey D., Allen, Kathleen S., Pavelko, Kevin D., Lindquist, Diana M., Dunn, R. Scott, Macura, Slobodan I., Johnson, Aaron J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278445/
https://ncbi.nlm.nih.gov/pubmed/22348089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031459
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