Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders

BACKGROUND: Serum autoantibodies against the water channel aquaporin-4 (AQP4) are important diagnostic biomarkers and pathogenic factors for neuromyelitis optica (NMO). However, AQP4-IgG are absent in 5-40% of all NMO patients and the target of the autoimmune response in these patients is unknown. S...

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Hlavní autoři: Mader, Simone, Gredler, Viktoria, Schanda, Kathrin, Rostasy, Kevin, Dujmovic, Irena, Pfaller, Kristian, Lutterotti, Andreas, Jarius, Sven, Di Pauli, Franziska, Kuenz, Bettina, Ehling, Rainer, Hegen, Harald, Deisenhammer, Florian, Aboul-Enein, Fahmy, Storch, Maria K, Koson, Peter, Drulovic, Jelena, Kristoferitsch, Wolfgang, Berger, Thomas, Reindl, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278385/
https://ncbi.nlm.nih.gov/pubmed/22204662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-184
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