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Efficacy and safety of prolonged-release melatonin for insomnia in middle-aged and elderly patients with hypertension: a combined analysis of controlled clinical trials
BACKGROUND: Add-on prolonged-release melatonin (PRM) in antihypertensive therapy has been shown to ameliorate nocturnal hypertension. Hypertension is a major comorbidity among insomnia patients. The efficacy and safety of PRM for primary insomnia in patients aged 55 years and older who are treated w...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Dove Medical Press
2012
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278206/ https://ncbi.nlm.nih.gov/pubmed/22346363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IBPC.S27240 |
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