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Efficacy and safety of prolonged-release melatonin for insomnia in middle-aged and elderly patients with hypertension: a combined analysis of controlled clinical trials

BACKGROUND: Add-on prolonged-release melatonin (PRM) in antihypertensive therapy has been shown to ameliorate nocturnal hypertension. Hypertension is a major comorbidity among insomnia patients. The efficacy and safety of PRM for primary insomnia in patients aged 55 years and older who are treated w...

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Detalhes bibliográficos
Main Authors: Lemoine, Patrick, Wade, Alan G, Katz, Amnon, Nir, Tali, Zisapel, Nava
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278206/
https://ncbi.nlm.nih.gov/pubmed/22346363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IBPC.S27240
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