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Asimadoline and its potential for the treatment of diarrhea-predominant irritable bowel syndrome: a review

Irritable bowel syndrome (IBS) is a multifactorial condition with principal symptoms of pain and altered bowel function. The kappa-opioid agonist asimadoline is being evaluated in Phase III as a potential treatment for IBS. Asimadoline, to date, has shown a good safety profile and the target Phase I...

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Autors principals: Mangel, Allen W, Hicks, Gareth A
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278196/
https://ncbi.nlm.nih.gov/pubmed/22346361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CEG.S23274
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