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Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia

BACKGROUND AND PURPOSE: Carbon monoxide (CO) is a gaseous second messenger produced when heme oxygenase (HO) enzymes catabolize heme. We have demonstrated that CO can be therapeutic in ischemia-reperfusion brain injury; however, it is unclear whether CO can also offer protection in permanent ischemi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Bing, Cao, Wangsen, Biswal, Shyam, Doré, Sylvain
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278075/
https://ncbi.nlm.nih.gov/pubmed/21852618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.607101
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