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Carbon monoxide-activated Nrf2 pathway leads to protection against permanent focal cerebral ischemia
BACKGROUND AND PURPOSE: Carbon monoxide (CO) is a gaseous second messenger produced when heme oxygenase (HO) enzymes catabolize heme. We have demonstrated that CO can be therapeutic in ischemia-reperfusion brain injury; however, it is unclear whether CO can also offer protection in permanent ischemi...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278075/ https://ncbi.nlm.nih.gov/pubmed/21852618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.607101 |
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