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Conformational changes induced in DNA by in vitro reaction with N-hydroxy-N-2-aminofluorene.

The conformation of DNA modified in vitro by the covalent binding of N-OH-AF was investigated by ultraviolet absorbance, circular dichroism and by radioimmunoassay using specific antibodies against Guo-AAF and nDNA-AAF. The results obtained by both physico-chemical and immunological methods are in a...

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Bibliografiske detaljer
Main Authors: Spodheim-Maurizot, M, Saint-Ruf, G, Leng, M
Format: Artigo
Sprog:Inglês
Udgivet: 1979
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC327800/
https://ncbi.nlm.nih.gov/pubmed/450711
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