Proteomic Identification of Betaig-h3 as a Lysophosphatidic Acid-Induced Secreted Protein of Human Mesenchymal Stem Cells: Paracrine Activation of A549 Lung Adenocarcinoma Cells by Betaig-h3

Lysophosphatidic acid (LPA) is enriched in the serum and malignant effusion of cancer patients and plays a key role in tumorigenesis and metastasis. LPA-activated mesenchymal stem cells promote tumorigenic potentials of cancer cells through a paracrine mechanism. LPA-conditioned medium (LPA CM) from...

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Bibliografiske detaljer
Main Authors: Shin, Sang Hun, Kim, Jaeyoon, Heo, Soon Chul, Kwon, Yang Woo, Kim, Young Mi, Kim, In-San, Lee, Taehoon G., Kim, Jae Ho
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277763/
https://ncbi.nlm.nih.gov/pubmed/22159598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.012385
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