A Simplified Immune Suppression Scheme Leads to Persistent Micro-dystrophin Expression in Duchenne Muscular Dystrophy Dogs

Highly abbreviated micro-dystrophin genes have been intensively studied for Duchenne muscular dystrophy (DMD) gene therapy. Following adeno-associated virus (AAV) gene transfer, robust microgene expression is achieved in murine DMD models in the absence of immune suppression. Interestingly, a recent...

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Detaylı Bibliyografya
Asıl Yazarlar: Shin, Jin-Hong, Yue, Yongping, Srivastava, Arun, Smith, Bruce, Lai, Yi, Duan, Dongsheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc. 2012
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277733/
https://ncbi.nlm.nih.gov/pubmed/21967249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.147
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