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A precise quantitation of gene number by saturation hybridization using cloned DNA.

This paper describes a precise method of gene titration as applied to the alpha- and beta-globin genes in the mouse. The three salient features of the method are: (i) the use of saturation hybridization in probe cDNA excess, (ii) the use of highly purified cDNA probes prepared by preparative hybridi...

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Publicat a:Nucleic Acids Res
Autors principals: Longacre, S S, Mach, B
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1979
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327770/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/450695/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/6.4.1241
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