A precise quantitation of gene number by saturation hybridization using cloned DNA.
This paper describes a precise method of gene titration as applied to the alpha- and beta-globin genes in the mouse. The three salient features of the method are: (i) the use of saturation hybridization in probe cDNA excess, (ii) the use of highly purified cDNA probes prepared by preparative hybridi...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1979
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327770/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/450695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/6.4.1241 |
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