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The receptor binding domain of botulinum neurotoxin serotype C binds phosphoinositides
Botulinum neurotoxins (BoNTs) are the most toxic proteins known for humans and animals with an extremely low LD(50) of ~ 1 ng/kg. BoNTs generally require a protein and a ganglioside on the cell membrane surface for binding, which is known as a “dual receptor” mechanism for host intoxication. Recent...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277684/ https://ncbi.nlm.nih.gov/pubmed/22120109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2011.11.004 |
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