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Soluble activin receptor type IIB treatment does not cause fat loss in mice with diet-induced obesity
The growth factor myostatin (MSTN) negatively regulates skeletal muscle mass. Mstn gene deletion in mice causes increased muscle mass, reduced adiposity and resistance to genetic or diet-induced obesity. Pharmacologic MSTN inhibition in mice also causes increased muscle mass and resistance to diet-i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277673/ https://ncbi.nlm.nih.gov/pubmed/22023380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1463-1326.2011.01520.x |
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