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A DNA-Based Nanomechanical Device Used to Characterize the Distortion of DNA by Apo-SoxR Protein

DNA-based nanomechanical devices can be used to characterize the action of DNA-distorting proteins. Here, we have constructed a device wherein two DNA triple crossover (TX) molecules are connected by a shaft, similar to a previous device that measured the binding free energy of integration host fact...

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Autors principals: Liu, Chunhua, Kim, Eunsuk, Demple, Bruce, Seeman, Nadrian C.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277648/
https://ncbi.nlm.nih.gov/pubmed/22257222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201196s
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