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Global kinetic analysis of proteolysis via quantitative targeted proteomics
Mass spectrometry-based proteomics is a powerful tool for identifying hundreds to thousands of posttranslational modifications in complex mixtures. However, it remains enormously challenging to simultaneously assess the intrinsic catalytic efficiencies (k(cat)/K(M)) of these modifications in the con...
Wedi'i Gadw mewn:
Prif Awduron: | , , , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
National Academy of Sciences
2012
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277568/ https://ncbi.nlm.nih.gov/pubmed/22308409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117158109 |
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