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Active transcription and essential role of RNA polymerase II at the centromere during mitosis

Transcription of the centromeric regions has been reported to occur in G1 and S phase in different species. Here, we investigate whether transcription also occurs and plays a functional role at the mammalian centromere during mitosis. We show the presence of actively transcribing RNA polymerase II (...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chan, F. Lyn, Marshall, Owen J., Saffery, Richard, Won Kim, Bo, Earle, Elizabeth, Choo, K. H. Andy, Wong, Lee H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277563/
https://ncbi.nlm.nih.gov/pubmed/22308327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108705109
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