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Monoallelic silencing and haploinsufficiency in early murine intestinal neoplasms
Studies of tumors from human familial adenomatous polyposis, sporadic colon cancer, and mouse and rat models of intestinal cancer indicate that the majority of early adenomas develop through loss of normal function of the Adenomatous polyposis coli (APC) gene. In murine models of familial adenomatou...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277532/ https://ncbi.nlm.nih.gov/pubmed/22308460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120753109 |
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