Vasoactive Intestinal Peptide Knockout (VIP KO) mouse model of sulfite-sensitive asthma: up-regulation of novel lung carbonyl reductase

BACKGROUND: We earlier reported spontaneous features of asthma in Vasoactive Intestinal Peptide knockout mice (VIP KO): 1) peribronchiolar airway inflammation, with accumulation of lymphocytes and eosinophils, 2) pro-inflammatory cytokine production of IL-5, IL-6, with IFN-γ, and 3) airway hyper-res...

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Bibliografiske detaljer
Main Authors: Szema, Anthony M, Hamidi, Sayyed A, Koller, Antonius, Martin, Dwight W
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277465/
https://ncbi.nlm.nih.gov/pubmed/22103391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-66
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