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Reactivity of antibodies to guanosine modified by the carcinogen N-acetoxy-N-2-acetylaminofluorene.

N-(guanosin-8-yl) acetylaminofluorene (Guo-AAF) was prepared by the reaction of N-acetoxy-N-2-acetylaminofluorene (AAAF) and guanosine. Antibodies to Guo-AAF were elicited in rabbits by immunization with bovine serum albumin-Guo-AAF conjugate. The antibodies were purified by affinity chromatography...

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Bibliographic Details
Main Authors: Guigues, M, Leng, M
Format: Artigo
Language:Inglês
Published: 1979
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC327724/
https://ncbi.nlm.nih.gov/pubmed/570700
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