Brush border Myosin Ia has tumor suppressor activity in the intestine

The loss of the epithelial architecture and cell polarity/differentiation is known to be important during the tumorigenic process. Here we demonstrate that the brush border protein Myosin Ia (MYO1A) is important for polarization and differentiation of colon cancer cells and is frequently inactivated...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mazzolini, Rocco, Dopeso, Higinio, Mateo-Lozano, Silvia, Chang, Wakam, Rodrigues, Paulo, Bazzocco, Sarah, Alazzouzi, Hafid, Landolfi, Stefania, Hernández-Losa, Javier, Andretta, Elena, Alhopuro, Pia, Espín, Eloy, Armengol, Manel, Tabernero, Josep, Ramón y Cajal, Santiago, Kloor, Matthias, Gebert, Johannes, Mariadason, John M., Schwartz, Simo, Aaltonen, Lauri A., Mooseker, Mark S., Arango, Diego
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277176/
https://ncbi.nlm.nih.gov/pubmed/22307608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108411109
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