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Brush border Myosin Ia has tumor suppressor activity in the intestine
The loss of the epithelial architecture and cell polarity/differentiation is known to be important during the tumorigenic process. Here we demonstrate that the brush border protein Myosin Ia (MYO1A) is important for polarization and differentiation of colon cancer cells and is frequently inactivated...
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| Главные авторы: | , , , , , , , , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277176/ https://ncbi.nlm.nih.gov/pubmed/22307608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108411109 |
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