Brush border Myosin Ia has tumor suppressor activity in the intestine

The loss of the epithelial architecture and cell polarity/differentiation is known to be important during the tumorigenic process. Here we demonstrate that the brush border protein Myosin Ia (MYO1A) is important for polarization and differentiation of colon cancer cells and is frequently inactivated...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Mazzolini, Rocco, Dopeso, Higinio, Mateo-Lozano, Silvia, Chang, Wakam, Rodrigues, Paulo, Bazzocco, Sarah, Alazzouzi, Hafid, Landolfi, Stefania, Hernández-Losa, Javier, Andretta, Elena, Alhopuro, Pia, Espín, Eloy, Armengol, Manel, Tabernero, Josep, Ramón y Cajal, Santiago, Kloor, Matthias, Gebert, Johannes, Mariadason, John M., Schwartz, Simo, Aaltonen, Lauri A., Mooseker, Mark S., Arango, Diego
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2012
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277176/
https://ncbi.nlm.nih.gov/pubmed/22307608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108411109
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