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Synthetic in vivo validation of gene network circuitry

Embryonic development is controlled by networks of interacting regulatory genes. The individual linkages of gene regulatory networks (GRNs) are customarily validated by functional cis-regulatory analysis, but an additional approach to validation is to rewire GRN circuitry to test experimentally pred...

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Detalhes bibliográficos
Main Authors: Damle, Sagar S., Davidson, Eric H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277137/
https://ncbi.nlm.nih.gov/pubmed/22238426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119905109
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