Twist contributes to hormone resistance in breast cancer by down-regulating estrogen receptor alpha

The role of estrogen receptor alpha (ER) in breast cancer development and as a primary clinical marker for breast cancer prognosis is well documented. In this study, we identified the oncogenic protein TWIST1 (Twist), which is over-expressed in high-grade breast cancers, as a potential negative regu...

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Main Authors: Vesuna, Farhad, Lisok, Ala, Kimble, Brian, Domek, John, Kato, Yoshinori, van der Groep, Petra, Artemov, Dmitri, Kowalski, Jeanne, Carraway, Hetty, van Diest, Paul, Raman, Venu
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276743/
https://ncbi.nlm.nih.gov/pubmed/22056872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.483
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