The abolishment of anesthesia-induced cognitive impairment by timely protection of mitochondria in the developing rat brain: the importance of free oxygen radicals and mitochondrial integrity

Early exposure to general anesthesia (GA) causes developmental neuroapoptosis in the mammalian brain and long-term cognitive impairment. Recent evidence suggests that GA also causes functional and morphological impairment of the immature neuronal mitochondria. Injured mitochondria could be a signifi...

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Detalhes bibliográficos
Main Authors: Boscolo, A, Starr, JA, Sanchez, Lunardi, N, DiGruccio, MR, Ori, C, Erisir, A, Trimmer, P, Bennett, J, Jevtovic-Todorovic
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276740/
https://ncbi.nlm.nih.gov/pubmed/22198380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.12.022
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